Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pyrexia
ADR ID BADD_A03683
ADR Hierarchy
08      General disorders and administration site conditions
08.05      Body temperature conditions
08.05.02      Febrile disorders
08.05.02.003      Pyrexia
Description An abnormal elevation of body temperature, usually as a result of a pathologic process. [MeSH]
MedDRA Code 10037660
MeSH ID D005334; D005334; D005334; D005334; D005335
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Chills & fever | Chills and fever | Drug fever | Febrile reaction | Fever | Fever chills | Fever of unknown origin | Heat production increased | Heat retention | High temperature | Intermittent pyrexia | Periodic fever | PUO | Pyrexia | Pyrexia abnormal | Pyrexia drug | Pyrexia NOS | Pyrexia of unknown origin | Pyrexia of unknown origin (excl puerperal) | Pyrexial | Reaction febrile | Slight fever | Spiking temperature | Slight temperature | Intermittent fever | Cotton fever | Febricula | Fluctuating fever | Chronic fever | Acute febrile illness | Feverish | Pyrogenic reaction | Fevers | Pyrexias | Hyperthermia | Hyperthermias
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Alanine aminotransferase 2Q28DB5Not Available
Alkaline phosphatase, placental typeP05187Not Available
Glutathione hydrolase 1 proenzymeP19440Not Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02497Avatrombopag0.001634%
BADD_D02498Abemaciclib--
BADD_D02500Alpelisib0.006927%
BADD_D02503Telotristat ethyl-
BADD_D02504Lorlatinib--
BADD_D02505Gilteritinib0.003730%
BADD_D02508Edaravone--
BADD_D02509Brigatinib0.001066%
BADD_D02510Rucaparib0.009591%
BADD_D02511Siponimod--
BADD_D02513Pegvaliase0.032041%
BADD_D02515Pexidartinib0.000799%
BADD_D02517Enasidenib0.002931%
BADD_D02520Baloxavir marboxil0.005787%
BADD_D02522Lithium citrate--
BADD_D02523Hydrocortisone succinate0.014354%
BADD_D02524Ivosidenib0.001598%
BADD_D02526Larotrectinib0.000799%
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